MSI introduced the B75IA-E33, a socket LGA1155 motherboard in the mini-ITX form-factor, based on Intel's business-oriented B75 Express chipset. The board has sufficient connectivity for space-saving business PCs, featuring Intel Small Business Advantage. The board also bears the Windows 8 compatibility label. It draws power from conventional 24-pin ATX and 4-pin CPU power connectors. The LGA1155 socket is powered by a 4-phase VRM. It is wired to two DIMM slots, supporting up to 16 GB of dual-channel DDR3-1600 MHz memory; and a PCI-Express 3.0 x16 slot.

The Intel B75 PCH gives out one SATA 6 Gb/s, and three SATA 3 Gb/s internal ports on the B75IA-E33. Display connectivity includes DVI, D-Sub, and HDMI. Other connectivity options include 6-channel HD audio with 7.1-channel optical SPDIF (TOSLINK) output, four USB 3.0 ports (two the rear panel, two by headers), gigabit Ethernet, a number of USB 2.0 ports, and mouse/keyboard combo PS/2 port. The board is driven by UEFI firmware. MSI did not give out pricing information.