Microsoft's documentation for client Windows version is not good. It lists 2 recent AMD vulnerabilities and registry keys to enable mitigations for them, but no statement whether the mitigation is enabled by default. The Microsoft CVE page for Inception suggests that some mitigations are enabled by default and you can enable more for "intra-process disclosure vectors". This would mirror what Linux has implemented with default "light" mode and heavier modes for when you have untrusted users or VMs.Lets hope you can disable the mitigations under Windows.
The registry keys are, as far as I understand, also mutually exclusive since they toggle different bits in the FeatureSettingsOverride value.
Their PowerShell module doesn't support AMD vulnerabilities either.
I hope that I'm interpreting this wrong, otherwise it's quite disappointing.