Probably not, but it's alot cleaner looking with a designated cable for the high power 12v connector.
I'm using a cablemod custom cable with my Prime Tx 1000 with a 4090 no issue's
I have a couple buddies using similar cables with the 3090ti with a corsair rmx and a seasonic prime gold 1000 also 0 issues.
i love small PSU with BIG power like this MSi a1000w or seasonic gx 1000w or corsair rme 1000w, because they have very small size (Dimensions: 140 mm (L) x 150 mm (W) x 86 mm (H), its perfect for lian li case, just like my owm PC, but corsair rmx series, seasonic prime gx px tx series, etc, all of them has very big size.....
i think all PSU builder must design very small size of PSU's but with big power, just like 3 example of that PSU....