Okay, okay, next time I'll profusely litter my post with
weasel words and heavy use of the words "usually", "often", and "normally".
That said, some people here (and other tech forums) enjoy making things as complicated as possible. With some thoughtful consideration beforehand, one can eliminate most of these complications that require specialized solutions.
I know that additives or alternate cooling liquids are useful in extreme situations, some of which certain PC builders put themselves into.
The International Space Station uses radiators with ammonia but I'm not going to recommend any PC builder to use ammonia. I wouldn't be surprised if some YouTuber has tried but not everything people do on YouTube should be copied.
So yeah, there's usually an exception to every rule. We all know that.
That said, for someone exploring custom cooling loops for normal PCs, it's best to keep things simple rather than to jump off into the deep end.
There are tons of tutorials and videos that describe custom cooling loops for PCs (many of them poorly authored and inaccurate). There are really a handful of basic guidelines to follow to make this a relatively simple project.