MSI announced two Radeon HD 7800 series graphics cards, both based on its TwinFrozr III cooling solution, albeit different variants. The R7870 TwinFrozr III from MSI uses a long PCB, and a meatier version of the TwinFrozr III cooler, which has been featured on high-end GeForce GTX 500 and Radeon HD 6900 series, in the past. It uses five 8 mm-thick nickel-plated copper heat pipes to convey heat drawn directly from the GPU, to a large aluminum fin array, ventilated by two 80 mm fans. This card is labeled to have factory-overclocked clock speeds.

The R7850 TwinFrozr III uses a shorter PCB, and a new, leaner version of the cooler, which has never been used by MSI before. It uses three 8 mm-thick n nickel-plated copper heat pipes to convey heat drawn directly from the GPU, to the heatsink. The two fans are nested within the aluminum fin stacks to maximize air-flow flow for heat dissipation. MSI boasts about how the noise output of this cooler is "only 27 dB" on load. Like the R7870 TF3, this card is factory-overclocked, too.