UPDATES:
I ordered the Zotac GF9300-G-E. The LGA-775 one with 3 SATA ports. If I had an I-series CPU handy I'd have gone with a different model. This build will still use the Q9550 I've been using in the past. I also went with the 480w KDM power supply.
http://www.directron.com/m7480dmmicro.html It uses 2 thermally-controlled 60mm fans. Hopefully they are quiet. I wanted to avoid cutting a hole in the bottom of the chassis and having to use large feet to allow airflow under it.
The HDD mount is designed to hold 1x 3.5" or 2x 2.5". A small SSD for the OS and a 500gb laptop spinner would provide plenty of storage for a gaming rig. One can always add an E-SATA or USB external drive for their media library. This mount's design uses rubber gromets to keep the drive isolated from the chassis to reduce noise.
There are now NO CHASSIS FANS! Only the CPU blower, GFX card blower, and 2 60mm in the PSU. All fans are thermally controlled. Each fan vents it's own heat directly out of the chassis. The case vents will be offset from the fans to also help reduce noise.
Prototype #2's base, cover, front and back plates are cut and once the board shows up friday, I can cut the expansion slots and i/o shield holes.
AIRFLOW:
The first fan to get cool inlet air is the GPU. Airflow passes over the harddrive(s) on the way to it so the drive does get some cooling. GPU blows hot air out of the chassis. A barrier down the middle of the chassis then directs remaining airflow towards the front where some is sucked out by the PSU. PSU blows hot air out of the chassis. The airflow continues over the northbridge heatsink then sucked through the CPU heatsink by the CPU blower. CPU blows hot air out of the chassis. No hot air is recirculated inside. I've spent alot of time testing many different configurations and this is an epic win by far.
I know I know... Pics soon.
EDIT - Here is a picture showing airflow through the chassis. The yellow line is the barrier I mentioned. It also serves to hold the riser card. The CPU fan shown is not what I'll be using. I'm using a blower as shown in the second pic. The HD5870 size cards will fit. Who knows if the 480w Micro-ATX can run it.