Thats why, at least for Contactonaut, a huge red paper inside the package states the "Do not use with Aluminium" along with some Xs.
I use liquid metal for about 8~9months now. Nickel palated CPU IHS and copper coldplate of the AIO block/pump package. Its expensive compound not only for its price on purchase but also because you need to do several applications when copper coldplates are at least the 1 side of the 2 contact surfaces. If both sides are copper I assume you need to replace it sooner, at least in half time.
As of performance... yes it is the best TIM you can get. I saw about 5~6C reduction on max temp (100% load) compared to ArcticSilver5.
Does it worth it? That depends on how you see things. For me yes it does, and I knew from the biginning that with copper needs re-application after short(er) period of time and not just once. I dont mind the cost, its too small among other expenses.
I saw der8ouer talking about it saying that needs replacement after 2 months for at least 2~3 times before you leave it for long. I find that for the first replacement it needs to be done on the month, not 2. For the second its ok to leave it 2~3months.
I first replace it after ~50 days and it was a bit late. Gallium had saturated copper in such amount that whats left behind was almost like very thin layer of dried compound, like a thin leave.
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It was a little hard to clean IHS but the AIO coldplate was a lot lot harder. I did some abrasion to remove it from copper surface from certain points/spots.
This is the final result.
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Next application
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After that I left it for 3 months and when I remove it again it was a lot easier for both as it wasnt dried this time. I'm on the 3rd month now (of 3rd application) and I will do it again next month. After that the copper saturation from gallium would be enough and slowed down for the TIM to last even longer.
You can see that AIO's coldplate is not as it was new, little scraped from "cleaning" process, but I did not see any cooling performance drop. I quess the high thermal conductivity of liquid metal makes up for it.
Another thing to consider other than cost, re-application and cleaning is the danger of shortcircuit components around the socket or the CPU itself. Needs extra care treatment, especially for beginners.