try looking into 3.3V monitoring on the Hwinfo64.
I have a combo of Seasonic PSU and Asus MoBo (several years older then yours though) and running in the issue of the 3.3V is running as low as 2.9 during 350W+ GPU load. MoBo detects it and shuts down the system.
The actual reason is quite quircky, since there is NO any high load on 3.3V line. I suppose that the PSU tries to use too clever wire-voltage-drop compensation for 12V that somehow negatively affect the 3.3 levels.
When I got those low 3.3 readings - I reseat the main 24-pin connector several times (both sides, MoBo and PSU) and after this the issue disappeared