In my opinion, you should look at the following things:
1) I hate glossy finishes. They will only look like crap in a short while, and you can expect people to have their keyboards close to the base of the stand at all times, which WILL lead to scratches. I'd suggest a different surface texture or material.
2) Connectors at the front is a bad idea (see 1). Desk width is usually not an issue, but desk depth is. The connectors should be either at the sides of the base or at another more creative location.
3) I work in Digital Signage, and as some other poster has stated some screens tend to heat up quite a lot. Depending on your design heat transfer and therefore accumulation between case and screen COULD become an issue, especially when you're marketing for enthusiasts who will want the lowest temperatures possible. Having a review uncover a bad delta value for CPU temp could wreck your reputation right at the start.
4) Adjustment is necessary. Even if I personally could do with the current design there are many people with crazy preferences when it comes to monitors. Some people also like theirs very high - maybe some sort of telescoping mechanism could be implemented as long as it doesn't affect the center of gravity?
5) The foot stand design is currently very ugly for my tastes. Personally, I'd go for someting more angular, and I'd probably go for a loop instead of a split at the back.
6) Your case looks somewhat good, although a little unrefined, yet it seems to have sharp edges. Sharp edges attached to a customer's hardware do not mix, even more so since many screens tend to have glossy surfaces. You should at least include some kind of standoff.
7) Cable Management. If going for enthusiasts I suspect that people will want a way to route the cables that leave the box in some way or another, be it mouse or keyboard. Especially the keyboard cable will be very long - and it's all on the table. Maybe you could implement some kind of cable compartment in the base where excess cabling from, say, the keyboard can go? Would go well with the loop from 5).
8) Focus on one design theme. Currently, the case itself is very angular and has a brushed metal finish, yet the base looks like cheap glossy plastic and is all round. I'm absolutely no designer, but it's very disharmonic to me.
As a sidenote - don't rule out a business application. Intel NUCs sell very well for us because they are space saving, so a diminutive business class case with no space for a GPU could actually sell nicely as well.
So this got longer than I expected, and not everything that I wrote might be constructive, but best of luck to you with your project