So much misinformation here.
1 - That motherboard will 100% guaranteed power on with the one 8-pin EPS connection, unless there is a different problem. The 4-pin connection is for extreme overclocking and even then it is unnecessary 97% of the time.
2 - That is an X570S motherboard, it is new enough to have a bios that support 5000-series CPUs without flashing anything.
3 - That PSU comes with one 4+4-pin EPS cable and one 8-pin EPS cable. Use either one to power the 8-pin connection on the motherboard.
4 - The motherboard should boot without any fans connected and give you a warning that the CPU fan is not running/detected. But I would absolutely connect the cooler fan to this header, I have run into stubborn motherboards before.
Now to address one beginner error I have seen numerous times and I don't see mentioned here. Remove the motherboard and make sure you haven't screwed up the standoffs in the case. You need to be absolutely sure you have the exact amount of standoffs to match the motherboard and that they are in the correct position. A misplaced standoff can short out the motherboard and cause a non-booting issue.
1. Should doesn't mean it's always the case. Some odd motherboards have a requirement that one connector be used before the other, and it also helps rule out a loose or damaged connector to try all options.
2. BIOS issues still exist, just because the CPU is supported doesn't mean it's guaranteed to work with his hardware (GPU/RAM, mostly) on a launch BIOS
3. Ideally, use both
4. I've used that board in person and it does stop at a fan error. It's a good way to ensure it stops at a BIOS level for troubleshooting instead of booting into an OS, tbh.
Issue is fixed. The ram had not been properly installed. The amount of force I need to put into the cards to get them into place was insane.
That's uncommon
Are these the RAM slots where one side clips in but the opposite side is just a slit? If so, you gotta make sure they're "Straight" before pushing down centrally, not one side then the other
