Well if you want something mobile then sure go with a standard PC case otherwise i would feel comfortable using either of those product's. I have worked with wood before and made various thing's, never had any issues with Pine or MDF/MDMF
Built everything from speaker cabinets to free standing structures, my grandfather was a carpenter.
If you are swapping components so frequently you should be looking at an open style tech bench anyways. Once i assemble a PC the only time i go in there is to clean it out every 6 months or so. I have mucked about with speaker assemblies more than PC build's in the past and still never had any issues
I don't see how a sealed WC loop or 200cfm -300cfm is going to cause any damage but whatever, to each their own. That's why there's more than 1 option at the hardware store and even more at the PC shop