Taking a look at this fairly light case, Antec has chosen to go with a simple look. Given it is part of the ISK range, such an approach makes sense as the chassis is meant for DIY builders and system integrators.
The front with Antec's logo in the top-right corner is out of sturdy plastic. It is completely flat and features a see-through strip running through it, behind which you will find a blue power LED we will see by the end of this review. Turning the ISK 600 around, you will find it to be all-black, like the interior.
Looking at the top, its cover is shaped out of a single steel panel with two identical openings on each side for some fresh air. Unfortunately, there are no dust filters, so dirt can enter the chassis freely. Due to the singular fan in the rear, which pulls air through these openings and pushes it out the back, odds are you will have to clean the interior more often than with other cases.
Antec also put the I/O into the front, and it consists of the usual pair of audio plugs and a USB 2.0 and a USB 3.0 plug. Antec should have gone with two USB 3.0 plus and an adapter for USB 2.0 compatibility instead. The current configuration means that you will essentially use plugs intended for four USB ports to power these properly. Next to the I/O are the Power and Reset buttons, identical in size. Watch out not to hit the Reset button by mistake when turning off your system or moving the computer around. In the top is a simple, but functional slimline ODD bay. It obviously lacks an eject button as such will be a part of any drive you install there.
You will find two expansion slots for the Mini-ITX motherboard in the rear, which would allow you to install dual-slot GPUs within the ISK 600. The individual covers are held in place by a traditional screw, each. In the opposite corner are a power plug since the standard-sized ATX PSU will be installed into the front, which has Antec route the plug to the back with a cable. Last, but not least, the only fan in the chassis is 120 mm large and pulls air out the back of the case. You may also install a liquid-cooling kit for your CPU there instead.
There is not much on the chassis' underside. As there are no openings, there are also no dust filters or mounting holes.