It's undoubtedly true that Itsuno is one of the key figures behind Capcom's best-in-class action and fighting games. Itsuno is notably known for his good work in the Devil May Cry series, created by Hideki Kamiya, but reaching its peak due to the fact that the Devil May Cry 3 was directed by him. Itsuno is also known for Dragon's Dogma, being his very own dream game, but the sequel turned out to be his last major project for Capcom.

Itsuno posted on Twitter, "At the end of August 2024, I will be leaving Capcom after 30 years and 5 months," "Thank you for your long-term support of the games and characters I have been responsible for. I hope you will continue to support Capcom's games and characters." He also added that he's not done with games yet, but is off to do his own thing. "From September, I will start developing a new game in a new environment. I hope to create fun, beautiful games that are as memorable as, or even more memorable than, the ones I have created so far."