In addition to the Radeon R7 300 series, AMD announced the Radeon R9 380 performance-segment graphics card. Available in 2 GB and 4 GB variants, with the 2 GB variant priced at $199, to compete with NVIDIA's GeForce GTX 960, and the 4 GB variant about $50 costlier, the card can play any of today's games at 1080p, with eye-candy maxed out, but can also play them at 1440p, with reasonably high settings.

Based on the 28 nm "Tonga" silicon, the R9 380 packs 1,792 stream processors based on the latest GCN 1.2 architecture, with 112 TMUs, 32 ROPs, and up to 4 GB of memory across a 256-bit wide memory interface. Its core is clocked at 970 MHz, with the memory at 5.70 GHz (GDDR5 effective), churning up 184 GB/s of memory bandwidth. The card's typical power draw is rated at 190W, it draws power from a pair of 6-pin PCIe power connectors.