The OSD can be accessed through a set of touch-sensitive "buttons" in the right corner of the bottom bezel. While I generally despise touch controls, I have to admit EIZO did a great job with these—they're very responsive and well organized, which makes navigating the OSD a breeze. As soon as you touch the controls, a set of quick menus will pop up on screen. All you then have to do is press the bezel on a spot beneath the menu you want to access.
The quick menus are, from left to right, input selection (USB-C, DisplayPort, HDMI 1, HDMI 2, Picture by Picture), picture profile selection (User1, User2, sRGB, Paper, Movie, DICOM), EcoView Settings, speaker volume, picture brightness, and main menu.
The main menu is split into five main segments—Color, Signal, Preferences, Languages, and Information.
The "Color" section is where we can switch between factory picture profiles, adjust the brightness and contrast (0-100), set the color temperature (from 4,000–10,000K in 500K increments) and gamma (1.8, 2.0, 2.2, and 2.4) and turn on the so-called Super Resolution feature, which aims to increase the perceived sharpness of low-res content. It can be set to Off, Low, or Standard. I didn't find any use for it and strongly suggest you leave it off—when it's on, fonts and object edges in 4K content actually look worse. The "Advanced Settings" menu contains several other options related to color reproduction and pixel response time—Overdrive (Off, Standard or Enhanced), Hue (-50 to +50), and Saturation (also -50 to +50). The "Gain" sub-menu allows us to manually adjust the amount of red, green, and blue color on a scale from 0–100. This can be useful for when you're trying to optimize the color performance without a calibrator or when you want to, say, filter out some of the blue color that increases eyestrain for some users.
The "Signal" menu is one most users won't ever need to dive into. The Picture Expansion option lets you adjust the pixel-mapping technique. It can be set to Aspect Ratio (aspect ratio of the input signal is maintained), Full Screen (the input signal is stretched over the entire panel), and Dot by Dot (1:1 pixel mapping). The Input Color Format option lets us pick between RGB and YUV color encoding systems. You'll want to keep it on "Auto". Same goes for the Input Range option, which can also be set to Full (corresponds to the RGB range of 0–255) and Limited (RGB range of 16–235).
The "Preferences" menu allows us to rotate the OSD, set the function of one of the USB 3.0 ports on the left side of the screen (it can work as a normal USB port or as a charging-only port), turn the Power Save feature on and off (keep it on), activate or deactivate the discrete front-facing white power LED, and reset the monitor.
The "Languages" menu is pretty self-explanatory, and the "Information" menu exposes the serial number and version of the monitor, its resolution and refresh rate, and total usage time. It would appear that I spent close to 120 hours testing and using this monitor.