Users beware: if you've updated your NVIDIA drivers to the
recently released 384.76 version and intend to play Watch Dogs 2, you might have a hard time doing so. Reports have surfaced that the latest NVIDIA drivers, which bring support to the "Rise Up" open-beta of "Lawbreakers" as well as support for "Spiderman: Homecoming - a VR Experience.", break startup on Ubisoft's game.
The issue doesn't appear to be listed on NVIDIA's 384.76 release notes (not even on the PDF), so it seems this issue largely flew under NVIDIA's radar. But if you've had problems with Wash (sorry, Watch) Dogs 2, be sure to check if you have the latest 384.76 drivers installed. That could be the source of the problem. Our own resident W1zzard himself ran into this problem, but no amount of steampunk wand waving was able to fix the issue. However, a fresh install of NVIDIA's previous driver release (
382.53) should let you go out to San Francisco again.
Edit: The issue is related to Ansel and can be fixed by starting C:\Program Files\NVIDIA Corporation\Ansel\Tools\NvCameraConfiguration.exe and selecting the "disabled" option at the bottom of the window.