The optical sensor is the PixelArt 3360, a very popular choice for high-end gaming mice, and it's easy to see why: the tracking is consistent and accurate, no matter the DPI or surface used.
For most of my testing, I've used the mouse at 1000 DPI, playing Counter-Strike Source, Dota2, Civilization 6, and World of Warcraft. It has been very accurate, with no stutter, lag or other strange behavior to report on.
The accuracy of the heart-rate sensor is on point provided there's a firm connection between the palm and the sensor itself; I double-checked the accuracy using a chest strap as well as a phone app that uses the phone's camera and flashlight to track the heart rate. The average heart rate was the same in all situations.
As stated before, the mouse is very comfortable to use with any grip. It should be noted, though, that the sensors require a firm connection between the mouse and the palm of your hand in order to be accurate. Users who prefer a claw or fingertip grip might not provide that full contact the optical sensor needs at all times. I feel that this problem could be alleviated (at least for claw-grip users) by placing the sensor hub about 0.5 cm lower, where the base of the palm easily rests.
Synthetic Benchmarks
For these tests, I had the mouse connected to a USB 3 port. Mouse acceleration was disabled in Windows, and I set a DPI of 1000 in the Mionix Hub software. I then moved the mouse side-to-side fast (three swipes, about 50 cm long, reasonably fast).
These are the raw counts from the mouse and are meant to gauge the accuracy of the reporting from the mouse. While it is normal to have small deviations from the mean, a larger deviation shows that tracking is not consistent and mouse movement may appear jittery.
It looks like deviations only appears when the polling rate is 500 Hz or higher.
Additionally, I would like to point out that I tested this mouse for about a month, and I used the highest polling rate available (1000Hz) and didn't notice any jittery movement or tracking misbehavior. However, I'm a casual gamer - somebody who relies on dead-on accuracy might feel differently.