MSI drew more than a few eyeballs at Computex 2018 when it showcased the X399 MEG Creation motherboard for AMD Ryzen Threadripper processors. With the advent of "new" Skylake-X Refresh processors by Intel, the company has a new high-end motherboard with the X299 MEG Creation. MSI appears to have toned down on the design from its X399-based product, although you still see the metal waveform design along the chipset heatsink that's contiguous with M.2 SSD heatsinks, the VRM heatsink, and the rear I/O shroud. The board draws power from a combination of 24-pin ATX, and two 8-pin EPS power connectors, conditioning it for the LGA2066 processor with a 14-phase VRM.

Expansion slots on the MSI X299 MEG Creation include four PCI-Express 3.0 x16, from which three are wired to the CPU, and the fourth one to the PCH. Between them are three M.2-2280 slots with PCI-Express 3.0 x4 wiring, each. You can add up to four more M.2-2280 SSDs with the included M.2-Xpander Aero accessory, which is a 4-slot M.2 riser with air-cooling, which made its debut with the X399 MEG Creation. Another star attraction with this board is Realtek 2.5 Gbps Ethernet, alongside an Intel i219-V powered 1 GbE interface, and an 802.11 ac + BT 5.0 WLAN. Another interesting accessory is the ThunderboltM3, a Thunderbolt 3.0 card with two type-C ports, and two DisplayPort connectors, for daisy chaining your displays. Storage connectivity, besides the seven M.2 slots, includes eight SATA 6 Gbps ports, and a U.2 port. This board could be priced around the $500-mark.