According to fresh benchmark numbers from someone on bilibili, Intel's Arc A380 cards perform even worse when paired with an AMD CPU compared to when paired with an Intel CPU. The card was tested using an AMD Ryzen 5 5600 on an ASUS TUF B550M motherboard paired with 16 GB of DDR4 3600 MHz memory. The Intel system it was tested against consisted of a Core i5-12400 on an ASUS TUF B660M motherboard with the same type of memory. Both test systems had resizable BAR support set to auto and above 4G decoding enabled. Windows 11 21H2 was also installed on both systems.

In every single game out of the 10 games tested, except League of Legends, the AMD system was behind the Intel system by anything from a mere one percent to as much as 15 percent. The worst performance disadvantage was in Forza Horizon 5 and Total War Three Kingdoms, both were 14 to 15 percent behind. The games that were tested, in order of the graph below are: League of Legends, Dota 2, Rainbow 6 Extraction, Watch Dogs Legions, Far Cry 6, Assassin's Creed Valhalla, Total War Three Kingdoms, Shadow of the Tomb Raider, CS:GO and Forza Horizon 5. For comparison, an NVIDIA GeForce GTX 1650 was also used, but only tested on the Intel based system and the Arc A380 only beat it on Total War Three Kingdoms, albeit by a seven percent margin. It appears Intel has a lot of work to do when it comes to its drivers, but at last right now, mixing Intel Arc graphics cards and AMD processors seems to be a bad idea.