Assembly
Placing the ITX mainboard is actually not as easy as you may think. The case's compact size does not give you much room to work with. The board did drop into place unharmed though - with a bit of nudging and squeezing. You better wire as much as you can in advance, but connecting everything is possible even if you do not.
You may go ahead and actually install the hard drive before putting the board down, but I sought to show you what it would be like to fill out the bays as a, for example, future upgrade. The metal parts need to be lined with the separately included stickers as an insulating barrier once the tray has been taken off. Once in place, simply screw the hard drive down and put the whole contraption back into place.
With everything installed, the ISK110 VESA is quite full, but the tall memory helps in keeping the mess created by the cables away from the center of the mini-ITX board. OEM coolers from both Intel and AMD should easily fit, but small enough aftermarket ones will be tough to find.
Finished Looks
The biggest difference between the ISK 100 and the ISK110 VESA becomes evident once everything has been assembled and after the cover has been put back in place. Thanks to the extruded metal mesh cover and removal of the fan, it can now hold more than just Intel Atoms or AMD Fusion based systems. You can clearly see that it tilts back a bit once the stand is screwed onto the chassis. This gives you easier access to the connectors at the front while also pushing down cables coming out the back, which helps in hiding them.
A blue power LED lights up once the system is turned on. Everything is where you would expect it to be in the rear, but having the PSU plug at the bottom of the device would have been nice.