MSI is ready with perhaps the industry's first SLI-supportive socket AM3 motherboard, certainly its first. The MSI NF750-G55 is based on NVIDIA nForce 750a SLI chipset, and has its AM3 socket powered by a 4+1 phase circuit, that supports Active Phase Switching that powers down redundant power phases when the load is low. The socket is wired to four DDR3 memory slots supporting up to DDR3-1800 by overclocking.

The nForce chipset connects to two PCI-Express 2.0 x16 slots that arrange as electrical dual x8 when both are populated for 2-way SLI. Apart from this, the chipset also embeds a GeForce 8300 class IGP as a fallback, or for GeForce Boost features. The IGP connects using D-Sub, HDMI, and DVI-D. Other expansion slots include two PCI-E x1, and one PCI. The chipset provides six SATA II ports in all, one of which is designated as eSATA on the rear-panel, next to one gigabit Ethernet, a number of USB 2.0 and FireWire ports, and 8-channel audio. The NF750-G50 has started selling in Europe for under 100 Euros.